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Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin

In this study, we assessed the super relaxed (SRX) state of myosin and sarcomeric protein phosphorylation in two pathological models of cardiomyopathy and in a near-physiological model of cardiac hypertrophy. The cardiomyopathy models differ in disease progression and severity and express the hypert...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Sitbon, Yoel H., Diaz, Francisca, Kazmierczak, Katarzyna, Liang, Jingsheng, Wangpaichitr, Medhi, Szczesna-Cordary, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142263/
https://ncbi.nlm.nih.gov/pubmed/34014247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012801
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