β-Asarone Ameliorates β-Amyloid–Induced Neurotoxicity in PC12 Cells by Activating P13K/Akt/Nrf2 Signaling Pathway

Accumulation of β-amyloid (Aβ) causes oxidative stress, which is the major pathological mechanism in Alzheimer’s disease (AD). β-asarone could reduce Aβ-induced oxidative stress and neuronal damage, but the molecular mechanism remains elusive. In this study, we used an Aβ-stimulated PC12 cell model...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Meng, Miaomiao, Zhang, Lijuan, AI, Di, Wu, Hongyun, Peng, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141729/
https://ncbi.nlm.nih.gov/pubmed/34040526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.659955
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