Ameliorating the Developmental Neurotoxicity of Chlorpyrifos: A Mechanisms-Based Approach in PC12 Cells

BACKGROUND: Organophosphate developmental neurotoxicity involves multiple mechanisms converging on neural cell replication and differentiation. OBJECTIVES: We evaluated mechanisms contributing to the adverse effects of chlorpyrifos (CPF) on DNA synthesis, cell number and size, and cell signaling med...

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Main Authors: Slotkin, Theodore A., MacKillop, Emiko A., Ryde, Ian T., Seidler, Frederic J.
格式: Artigo
語言:Inglês
出版: National Institute of Environmental Health Sciences 2007
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964921/
https://ncbi.nlm.nih.gov/pubmed/17805420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10194
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