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Experimental study on the neurotoxic effect of β-amyloid on the cytoskeleton of PC12 cells

The aim of the present study was to establish a cell model of Alzheimer's disease (AD) and investigate the neurotoxic effects of β-amyloid (Aβ) on the cytoskeleton. PC12 cells were cultured and treated with Aβ(25-35), and cell survival was analyzed with the MTT assay. Cell apoptosis was visuali...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Wang, Lai, Cao, Jingjing, Shi, Zhenyu, Fan, Wenjuan, Liu, Hongliang, Deng, Jinbo, Deng, Jiexin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846656/
https://ncbi.nlm.nih.gov/pubmed/29436599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3467
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