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Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model

Various anticoagulant properties have been associated with hydroxyethyl starch (HES). However, the mechanism remains unclear and it has not been fully considered whether these properties are beyond the dilutional effect itself. The aim of this study was to reproduce the coagulopathy induced by HES a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Azumaguchi, Ryu, Tokinaga, Yasuyuki, Kazuma, Satoshi, Kimizuka, Motonobu, Hamada, Kosuke, Sato, Tomoe, Yamakage, Michiaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140106/
https://ncbi.nlm.nih.gov/pubmed/34021192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89889-8
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