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Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model

Various anticoagulant properties have been associated with hydroxyethyl starch (HES). However, the mechanism remains unclear and it has not been fully considered whether these properties are beyond the dilutional effect itself. The aim of this study was to reproduce the coagulopathy induced by HES a...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Azumaguchi, Ryu, Tokinaga, Yasuyuki, Kazuma, Satoshi, Kimizuka, Motonobu, Hamada, Kosuke, Sato, Tomoe, Yamakage, Michiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140106/
https://ncbi.nlm.nih.gov/pubmed/34021192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89889-8
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