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Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model

Various anticoagulant properties have been associated with hydroxyethyl starch (HES). However, the mechanism remains unclear and it has not been fully considered whether these properties are beyond the dilutional effect itself. The aim of this study was to reproduce the coagulopathy induced by HES a...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Azumaguchi, Ryu, Tokinaga, Yasuyuki, Kazuma, Satoshi, Kimizuka, Motonobu, Hamada, Kosuke, Sato, Tomoe, Yamakage, Michiaki
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140106/
https://ncbi.nlm.nih.gov/pubmed/34021192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89889-8
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