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Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

Aggregation of α-synuclein (α-syn) is closely linked to Parkinson’s disease (PD) and the related synucleinopathies. Aggregates spread through the brain during the progression of PD, but the mechanism by which this occurs is still not known. One possibility is a self-propagating, templated-seeding me...

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Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Sang, Jason C., Hidari, Eric, Meisl, Georg, Ranasinghe, Rohan T., Spillantini, Maria Grazia, Klenerman, David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139990/
https://ncbi.nlm.nih.gov/pubmed/34021258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02126-w
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