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Mild Cu(OTf)(2)-mediated C-glycosylation with Chelation-Assisted Picolinate as a Leaving Group

C-glycosylation reactions of glycosyl picolinates with allyltrimethylsilane or silyl enol ethers were developed. Picolinate as a chelation-assisted leaving group could be activated by Cu(OTf)(2) and avoided the use of harsh Lewis acids. The glycosylations were operated under mild neutral conditions...

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Bibliografische gegevens
Gepubliceerd in:J Org Chem
Hoofdauteurs: Ye, Wenjing, Stevens, Christopher M., Wen, Peng, Simmons, Christopher J., Tang, Weiping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138965/
https://ncbi.nlm.nih.gov/pubmed/32691596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01041
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