Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration

BACKGROUND: The endoglycosidase heparanase which degrades heparan sulfate proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders. However, the function and underlying mechanism of heparanase in acute pancreatitis remain poorly understood. Here, we investigated the interp...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Microbiome
Autori principali: Lei, Yuanyuan, Tang, Li, Liu, Shuang, Hu, Shiping, Wu, Lingyi, Liu, Yaojiang, Yang, Min, Huang, Shengjie, Tang, Xuefeng, Tang, Tao, Zhao, Xiaoyan, Vlodavsky, Israel, Zeng, Shuo, Tang, Bo, Yang, Shiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138927/
https://ncbi.nlm.nih.gov/pubmed/34016163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-021-01065-2
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