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Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA polymerase
The exocyclic amines of nucleobases can undergo deamination by various DNA damaging agents such as reactive oxygen species, nitric oxide, and water. The deamination of guanine and adenine generates the promutagenic xanthine and hypoxanthine, respectively. The exocyclic amines of bases in DNA are hyd...
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| Vydáno v: | Biochem J |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138886/ https://ncbi.nlm.nih.gov/pubmed/33258913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200800 |
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