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Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase η
Nitrogen mustards are among the first modern anticancer chemotherapeutics that are still widely used as non-specific anticancer alkylating agents. While the mechanism of action of mustard drugs involves the generation of DNA interstrand cross-links, the predominant lesions produced by these drugs ar...
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| Publicado no: | Biochem J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7746141/ https://ncbi.nlm.nih.gov/pubmed/33175093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200767 |
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