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A statistical framework for predicting critical regions of p53-dependent enhancers
P53 is the ‘guardian of the genome’ and is responsible for regulating cell cycle and apoptosis. The genomic p53 binding regions, where activating transcriptional factors and cofactors like p300 simultaneously bind, are called ‘p53-dependent enhancers’, which play an important role in tumorigenesis....
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| Publicado no: | Brief Bioinform |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138796/ https://ncbi.nlm.nih.gov/pubmed/32392580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbaa053 |
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