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A Pretraining-Retraining Strategy of Deep Learning Improves Cell-Specific Enhancer Predictions

Deciphering the code of cis-regulatory element (CRE) is one of the core issues of today’s biology. Enhancers are distal CREs and play significant roles in gene transcriptional regulation. Although identifications of enhancer locations across the whole genome [discriminative enhancer predictions (DEP...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Niu, Xiaohui, Yang, Kun, Zhang, Ge, Yang, Zhiquan, Hu, Xuehai
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960260/
https://ncbi.nlm.nih.gov/pubmed/31969903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01305
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