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A statistical framework for predicting critical regions of p53-dependent enhancers
P53 is the ‘guardian of the genome’ and is responsible for regulating cell cycle and apoptosis. The genomic p53 binding regions, where activating transcriptional factors and cofactors like p300 simultaneously bind, are called ‘p53-dependent enhancers’, which play an important role in tumorigenesis....
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| I publikationen: | Brief Bioinform |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138796/ https://ncbi.nlm.nih.gov/pubmed/32392580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbaa053 |
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