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CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells
Pregnenolone (P5) promotes prostate cancer cell growth, and de novo synthesis of intratumoural P5 is a potential cause of development of castration resistance. Immune cells can also synthesize P5 de novo. Despite its biological importance, little is known about P5's mode of actions, which appea...
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| Publicado no: | iScience |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138728/ https://ncbi.nlm.nih.gov/pubmed/34036248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102485 |
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