Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth

Here, using single-cell RNA sequencing, we examine the stromal compartment in murine melanoma and draining lymph nodes (LNs) at points across tumor development, providing data at http://www.teichlab.org/data/. Naive lymphocytes from LNs undergo activation and clonal expansion within the tumor, befor...

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Udgivet i:Cell Rep
Main Authors: Davidson, Sarah, Efremova, Mirjana, Riedel, Angela, Mahata, Bidesh, Pramanik, Jhuma, Huuhtanen, Jani, Kar, Gozde, Vento-Tormo, Roser, Hagai, Tzachi, Chen, Xi, Haniffa, Muzlifah A., Shields, Jacqueline D., Teichmann, Sarah A.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242909/
https://ncbi.nlm.nih.gov/pubmed/32433953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107628
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