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Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

SARS‐CoV‐2 is the coronavirus responsible for the COVID‐19 pandemic. Proteases are central to the infection process of SARS‐CoV‐2. Cleavage of the spike protein on the virus's capsid causes the conformational change that leads to membrane fusion and viral entry into the target cell. Since inhib...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Bollavaram, Keval, Leeman, Tiffanie H., Lee, Maggie W., Kulkarni, Akhil, Upshaw, Sophia G., Yang, Jiabei, Song, Hannah, Platt, Manu O.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138523/
https://ncbi.nlm.nih.gov/pubmed/33786919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4073
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