Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

Immunization with radiation-attenuated sporozoites (RAS) has been shown to protect against malaria infection, primarily through CD8 T cell responses, but protection is limited based on parasite strain. Therefore, while CD8 T cells are an ideal effector population target for liver stage malaria vacci...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Tucker, Kenneth D., Schanen, Brian C., Phares, Timothy W., Sassano, Emily, Terry, Frances E., Hindocha, Pooja, Moise, Leonard, Kotraiah, Vinayaka, Martin, William D., De Groot, Anne S., Drake, Donald R., Gutierrez, Gabriel M., Noe, Amy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138313/
https://ncbi.nlm.nih.gov/pubmed/34025684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.684116
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