Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization

The hurdles to effective blood stage malaria vaccine design include immune evasion tactics used by the parasite such as redundant invasion pathways and antigen variation among circulating parasite strains. While blood stage malaria vaccine development primarily focuses on eliciting optimal humoral r...

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Udgivet i:Front Immunol
Main Authors: Kotraiah, Vinayaka, Phares, Timothy W., Terry, Frances E., Hindocha, Pooja, Silk, Sarah E., Nielsen, Carolyn M., Moise, Leonard, Tucker, Kenneth D., Ashfield, Rebecca, Martin, William D., De Groot, Anne S., Draper, Simon J., Gutierrez, Gabriel M., Noe, Amy R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294059/
https://ncbi.nlm.nih.gov/pubmed/34305923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.690348
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