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A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers

The management of Parkinson's disease (PD) is frequently compromised by complications induced by dopaminergic treatment such as involuntary movements (dyskinesias) and psychosis. Mesdopetam (IRL790) is a novel dopamine D3 receptor antagonist developed for the management of complications of ther...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Sjöberg, Folke, Waters, Susanna, Löfberg, Boel, Sonesson, Clas, Waters, Nicholas, Tedroff, Joakim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137807/
https://ncbi.nlm.nih.gov/pubmed/34018344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.792
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