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A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers

The management of Parkinson's disease (PD) is frequently compromised by complications induced by dopaminergic treatment such as involuntary movements (dyskinesias) and psychosis. Mesdopetam (IRL790) is a novel dopamine D3 receptor antagonist developed for the management of complications of ther...

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Publicado en:Pharmacol Res Perspect
Autores principales: Sjöberg, Folke, Waters, Susanna, Löfberg, Boel, Sonesson, Clas, Waters, Nicholas, Tedroff, Joakim
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137807/
https://ncbi.nlm.nih.gov/pubmed/34018344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.792
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