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Chr20q amplification defines a distinct molecular subtype of microsatellite stable colorectal cancer

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the US. About 15% of CRCs are associated with microsatellite instability (MSI) due to loss of function in the DNA mismatch repair pathway. This subgroup of patients has better survival rates and is more sensitive to immuno...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Zhang, Baoyi, Yao, Kevin, Zhou, Emily, Zhang, Lanjing, Cheng, Chao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137593/
https://ncbi.nlm.nih.gov/pubmed/33619118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-4009
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