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Chr20q amplification defines a distinct molecular subtype of microsatellite stable colorectal cancer

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the US. About 15% of CRCs are associated with microsatellite instability (MSI) due to loss of function in the DNA mismatch repair pathway. This subgroup of patients has better survival rates and is more sensitive to immuno...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Zhang, Baoyi, Yao, Kevin, Zhou, Emily, Zhang, Lanjing, Cheng, Chao
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137593/
https://ncbi.nlm.nih.gov/pubmed/33619118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-4009
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