Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions

Sporadic angiosarcomas (ASs) are aggressive vascular sarcomas whose rarity and genomic complexity present significant obstacles in deciphering the pathogenic significance of individual genetic alterations. Numerous fusion genes have been identified across multiple types of cancers, but their existen...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Kim, Jong Hyuk, Megquier, Kate, Thomas, Rachael, Sarver, Aaron L., Song, Jung Min, Kim, Yoon Tae, Cheng, Nuojin, Schulte, Ashley J., Linden, Michael A., Murugan, Paari, Oseth, LeAnn, Forster, Colleen L., Elvers, Ingegerd, Swofford, Ross, Turner-Maier, Jason, Karlsson, Elinor K., Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137578/
https://ncbi.nlm.nih.gov/pubmed/33649193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0937
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