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Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma

The CXCR4/CXCL12 axis plays an important role in cell locomotion and metastasis in many cancers. In this study, we hypothesized that the CXCR4/CXCL12 axis promotes migration and invasion of canine hemangiosarcoma (HSA) cells. Transcriptomic analysis across 12 HSA cell lines and 58 HSA whole tumour t...

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Detalhes bibliográficos
Publicado no:Vet Comp Oncol
Main Authors: Im, KeumSoon, Graef, Ashley J., Breen, Matthew, Lindblad-Toh, Kerstin, Modiano, Jaime F., Kim, Jong-Hyuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199805/
https://ncbi.nlm.nih.gov/pubmed/26337509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12165
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