Identification of Three Molecular and Functional Subtypes in Canine Hemangiosarcoma through Gene Expression Profiling and Progenitor Cell Characterization

Canine hemangiosarcomas have been ascribed to an endothelial origin based on histologic appearance; however, recent findings suggest that these tumors may arise instead from hematopoietic progenitor cells. To clarify this ontogenetic dilemma, we used genome-wide expression profiling of primary heman...

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Detalhes bibliográficos
Main Authors: Gorden, Brandi H., Kim, Jong-Hyuk, Sarver, Aaron L., Frantz, Aric M., Breen, Matthew, Lindblad-Toh, Kerstin, O'Brien, Timothy D., Sharkey, Leslie C., Modiano, Jaime F., Dickerson, Erin B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969990/
https://ncbi.nlm.nih.gov/pubmed/24525151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.025
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