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Identification of Three Molecular and Functional Subtypes in Canine Hemangiosarcoma through Gene Expression Profiling and Progenitor Cell Characterization

Canine hemangiosarcomas have been ascribed to an endothelial origin based on histologic appearance; however, recent findings suggest that these tumors may arise instead from hematopoietic progenitor cells. To clarify this ontogenetic dilemma, we used genome-wide expression profiling of primary heman...

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Main Authors: Gorden, Brandi H., Kim, Jong-Hyuk, Sarver, Aaron L., Frantz, Aric M., Breen, Matthew, Lindblad-Toh, Kerstin, O'Brien, Timothy D., Sharkey, Leslie C., Modiano, Jaime F., Dickerson, Erin B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969990/
https://ncbi.nlm.nih.gov/pubmed/24525151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.025
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