Tet2 inactivation enhances the anti-tumor activity of tumor-infiltrating lymphocytes

Inactivation of tumor-infiltrating lymphocytes (TIL) is one of the mechanisms mitigating anti-tumor immunity during tumor onset and progression. Epigenetic abnormalities are regarded as a major culprit contributing to the dysfunction of TILs within tumor microenvironments. In this study, we used a m...

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Vydáno v:Cancer Res
Hlavní autoři: Lee, Minjung, Li, Jianfang, Li, Jia, Fang, Shaohai, Zhang, Joanna, Vo, Anh Tran Tram, Han, Wei, Zeng, Hongxiang, Isgandarova, Sevinj, Martinez-Moczygemba, Margarita, Zhou, Yubin, Sun, Deqiang, Huang, Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137576/
https://ncbi.nlm.nih.gov/pubmed/33589517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-3213
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