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Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments

Small-cell lung cancers derive from pulmonary neuroendocrine cells, which have stem-like properties to reprogram into other cell types upon lung injury. It is difficult to uncouple transcriptional plasticity of these transformed cells from genetic changes that evolve in primary tumors or secondary m...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Schaff, Dylan L., Singh, Shambhavi, Kim, Kee-Beom, Sutcliffe, Matthew D., Park, Kwon-Sik, Janes, Kevin A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137564/
https://ncbi.nlm.nih.gov/pubmed/33531375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1036
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