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Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments

Small-cell lung cancers derive from pulmonary neuroendocrine cells, which have stem-like properties to reprogram into other cell types upon lung injury. It is difficult to uncouple transcriptional plasticity of these transformed cells from genetic changes that evolve in primary tumors or secondary m...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Schaff, Dylan L., Singh, Shambhavi, Kim, Kee-Beom, Sutcliffe, Matthew D., Park, Kwon-Sik, Janes, Kevin A.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137564/
https://ncbi.nlm.nih.gov/pubmed/33531375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1036
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