Loss of aryl hydrocarbon receptor promotes colon tumorigenesis in Apc(S580/+); Kras(G12D/+) mice

The mutational genetic landscape of colorectal cancer has been extensively characterized, however, the ability of “cooperation response genes” to modulate the function of cancer “driver” genes remains largely unknown. In this study, we investigate the role of aryl hydrocarbon receptor (AhR), a ligan...

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Pubblicato in:Mol Cancer Res
Autori principali: Han, Huajun, Davidson, Laurie A., Hensel, Martha, Yoon, Grace, Landrock, Kerstin, Allred, Clinton, Jayaraman, Arul, Ivanov, Ivan, Safe, Stephen H., Chapkin, Robert S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137548/
https://ncbi.nlm.nih.gov/pubmed/33495399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0789
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