Loss of aryl hydrocarbon receptor promotes colon tumorigenesis in Apc(S580/+); Kras(G12D/+) mice

The mutational genetic landscape of colorectal cancer has been extensively characterized, however, the ability of “cooperation response genes” to modulate the function of cancer “driver” genes remains largely unknown. In this study, we investigate the role of aryl hydrocarbon receptor (AhR), a ligan...

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Foilsithe in:Mol Cancer Res
Main Authors: Han, Huajun, Davidson, Laurie A., Hensel, Martha, Yoon, Grace, Landrock, Kerstin, Allred, Clinton, Jayaraman, Arul, Ivanov, Ivan, Safe, Stephen H., Chapkin, Robert S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137548/
https://ncbi.nlm.nih.gov/pubmed/33495399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0789
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