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Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever
Importing necessary metabolites into the mitochondrial matrix is a crucial step of fuel choice during stress adaptation. Branched chain-amino acids (BCAAs) are essential amino acids needed for anabolic processes, but they are also imported into the mitochondria for catabolic reactions. What controls...
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| Izdano u: | eLife |
|---|---|
| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8137140/ https://ncbi.nlm.nih.gov/pubmed/33944778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66865 |
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