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FreeHi-C simulates high fidelity Hi-C data for benchmarking and data augmentation
Ability to simulate high-throughput chromatin conformation (Hi-C) data is foundational for benchmarking Hi-C data analysis methods. Here we present a non-parametric strategy named FreeHi-C to simulate Hi-C data from the interacting genome fragments. Data from FreeHi-C exhibit high fidelity to biolog...
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| Pubblicato in: | Nat Methods |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8136837/ https://ncbi.nlm.nih.gov/pubmed/31712779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0624-3 |
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