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FreeHi-C Spike-in Simulations for Benchmarking Differential Chromatin Interaction Detection

High-throughput genome-wide chromatin conformation capture assay (Hi-C) is routinely used to profile long-range genomic interactions and three-dimensional organization of genomes. A key application of Hi-C is the comparative analysis of genomic interactions across different time points, cellular con...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Zheng, Ye, Zhou, Peigen, Keleş, Sündüz
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855360/
https://ncbi.nlm.nih.gov/pubmed/32663510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2020.07.001
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