Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis

Fragments of mitochondrial DNA are known to get inserted into nuclear DNA to form NUMTs, i.e. nuclear pseudogenes of the mtDNA. The insertion of a NUMT is a rare event. Hundreds of pseudogenes have been cataloged in the human genome. NUMTs are, in essence, a special type of mutation with their own i...

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Publicado en:Mitochondrion
Main Authors: Gunbin, Konstantin, Peshkin, Leonid, Popadin, Konstantin, Annis, Sofia, Ackermann, Rebecca R., Khrapko, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136834/
https://ncbi.nlm.nih.gov/pubmed/27979772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2016.12.001
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