DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history. Despite early identification of ACE2 as the receptor for viral spike protein, much remains to be understood about the molecular events behind viral dissemination. We evaluated the contribution of C-type lectin recept...

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Pubblicato in:PLoS Pathog
Autori principali: Thépaut, Michel, Luczkowiak, Joanna, Vivès, Corinne, Labiod, Nuria, Bally, Isabelle, Lasala, Fátima, Grimoire, Yasmina, Fenel, Daphna, Sattin, Sara, Thielens, Nicole, Schoehn, Guy, Bernardi, Anna, Delgado, Rafael, Fieschi, Franck
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136665/
https://ncbi.nlm.nih.gov/pubmed/34015061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009576
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