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Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies

Precursor messenger RNA (pre-mRNA) splicing is a fundamental step in eukaryotic gene expression that systematically removes non-coding regions (introns) and ligates coding regions (exons) into a continuous message (mature mRNA). This process is highly regulated and can be highly flexible through a p...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Li, Dunhui, McIntosh, Craig Stewart, Mastaglia, Frank Louis, Wilton, Steve Donald, Aung-Htut, May Thandar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136212/
https://ncbi.nlm.nih.gov/pubmed/34016162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-021-00240-7
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