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Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing
Spinocerebellar ataxia type 3 (SCA3) is a devastating neurodegenerative disease for which there is currently no cure, nor effective treatment strategy. One of nine polyglutamine disorders known to date, SCA3 is clinically heterogeneous and the main feature is progressive ataxia, which in turn affect...
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| Vydáno v: | Int J Mol Sci |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6862616/ https://ncbi.nlm.nih.gov/pubmed/31683630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215434 |
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