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Single human oocyte transcriptome analysis reveals distinct maturation stage‐dependent pathways impacted by age

Female fertility is inversely correlated with maternal age due to a depletion of the oocyte pool and a reduction in oocyte developmental competence. Few studies have addressed the effect of maternal age on the human mature oocyte (MII) transcriptome, which is established during oocyte growth and mat...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Llonch, Sílvia, Barragán, Montserrat, Nieto, Paula, Mallol, Anna, Elosua‐Bayes, Marc, Lorden, Patricia, Ruiz, Sara, Zambelli, Filippo, Heyn, Holger, Vassena, Rita, Payer, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8135014/
https://ncbi.nlm.nih.gov/pubmed/33908703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13360
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