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SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes
Spatially resolved gene expression profiles are key to understand tissue organization and function. However, spatial transcriptomics (ST) profiling techniques lack single-cell resolution and require a combination with single-cell RNA sequencing (scRNA-seq) information to deconvolute the spatially in...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8136778/ https://ncbi.nlm.nih.gov/pubmed/33544846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab043 |
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