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Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response

Virus-infected cells and cancers share metabolic commonalities that stem from their insatiable need to replicate while evading the host immune system. These similarities include hijacking signaling mechanisms that induce metabolic rewiring in the host to up-regulate nucleotide metabolism and, in par...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Ariav, Yarden, Ch’ng, James H, Christofk, Heather R., Ron-Harel, Noga, Erez, Ayelet
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133749/
https://ncbi.nlm.nih.gov/pubmed/34138729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg6165
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