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Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response

Virus-infected cells and cancers share metabolic commonalities that stem from their insatiable need to replicate while evading the host immune system. These similarities include hijacking signaling mechanisms that induce metabolic rewiring in the host to up-regulate nucleotide metabolism and, in par...

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Pubblicato in:Sci Adv
Autori principali: Ariav, Yarden, Ch’ng, James H, Christofk, Heather R., Ron-Harel, Noga, Erez, Ayelet
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133749/
https://ncbi.nlm.nih.gov/pubmed/34138729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg6165
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