CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

Indigenous people worldwide are at high risk of developing severe influenza disease. HLA-A*24:02 allele, highly prevalent in Indigenous populations, is associated with influenza-induced mortality, although the basis for this association is unclear. Here, we define CD8(+) T-cell immune landscapes aga...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Hensen, Luca, Illing, Patricia T., Bridie Clemens, E., Nguyen, Thi H. O., Koutsakos, Marios, van de Sandt, Carolien E., Mifsud, Nicole A., Nguyen, Andrea T., Szeto, Christopher, Chua, Brendon Y., Halim, Hanim, Rizzetto, Simone, Luciani, Fabio, Loh, Liyen, Grant, Emma J., Saunders, Phillipa M., Brooks, Andrew G., Rockman, Steve, Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Wakim, Linda M., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Jackson, David C., Flanagan, Katie L., Rossjohn, Jamie, Gras, Stephanie, Davies, Jane, Miller, Adrian, Tong, Steven Y. C., Purcell, Anthony W., Kedzierska, Katherine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132304/
https://ncbi.nlm.nih.gov/pubmed/34006841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23212-x
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