Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma

PURPOSE: Malignant pleural mesothelioma (MPM) is an aggressive cancer associated with poor prognosis. CRS-207 is a live-attenuated Listeria monocytogenes engineered to express mesothelin, a tumor-associated antigen highly expressed in MPM. CRS-207 induces antitumor immune responses and increases sus...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Hassan, Raffit, Alley, Evan, Kindler, Hedy, Antonia, Scott, Jahan, Thierry, Honarmand, Somayeh, Nair, Nitya, Whiting, Chan C., Enstrom, Amanda, Lemmens, Ed, Tsujikawa, Takahiro, Kumar, Sushil, Choe, Gina, Thomas, Anish, McDougall, Katherine, Murphy, Aimee L., Jaffee, Elizabeth, Coussens, Lisa M., Brockstedt, Dirk G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132300/
https://ncbi.nlm.nih.gov/pubmed/31263030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0070
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