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Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs
Of late, targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting...
Uloženo v:
| Vydáno v: | J Biol Chem |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131913/ https://ncbi.nlm.nih.gov/pubmed/33839157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100647 |
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