Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction

Three-dimensional genome organisation and replication timing are known to be correlated, however, it remains unknown whether nuclear architecture overall plays an instructive role in the replication-timing programme and, if so, how. Here we demonstrate that RIF1 is a molecular hub that co-regulates...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Gnan, Stefano, Flyamer, Ilya M., Klein, Kyle N., Castelli, Eleonora, Rapp, Alexander, Maiser, Andreas, Chen, Naiming, Weber, Patrick, Enervald, Elin, Cardoso, M. Cristina, Bickmore, Wendy A., Gilbert, David M., Buonomo, Sara C. B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131703/
https://ncbi.nlm.nih.gov/pubmed/34006872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22899-2
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