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AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis

Fibrosis is a hallmark of heart disease independent of etiology and is thought to contribute to impaired cardiac dysfunction and development of heart failure. However, the underlying mechanisms that regulate the differentiation of fibroblasts to myofibroblasts and fibrotic responses remain incomplet...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Francisco, Jamie, Zhang, Yu, Nakada, Yasuki, Jeong, Jae Im, Huang, Chun-Yang, Ivessa, Andreas, Oka, Shinichi, Babu, Gopal J., Del Re, Dominic P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131354/
https://ncbi.nlm.nih.gov/pubmed/34006931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89989-5
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