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Enantioselective Nickel-Catalyzed Alkyne–Azide Cycloaddition by Dynamic Kinetic Resolution

The triazole heterocycle has been widely adopted as an isostere for the amide bond. Many native amides are α-chiral, being derived from amino acids. This makes α-N-chiral triazoles attractive building blocks. This report describes the first enantioselective triazole synthesis that proceeds via nicke...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Chem Soc
मुख्य लेखकों: Liu, En-Chih, Topczewski, Joseph J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130861/
https://ncbi.nlm.nih.gov/pubmed/33798335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c01354
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