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Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

AIMS: Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment, while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug, has antioxidant and anti‐inflammatory properties. This study was designed to investigate the protective effect...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Taghizadeh, Fatemeh, Hosseinimehr, Seyed Jalal, Zargari, Mehryar, Karimpour Malekshah, Abbasali, Mirzaei, Mansoureh, Talebpour Amiri, Fereshteh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130655/
https://ncbi.nlm.nih.gov/pubmed/34003600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.788
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